Possibly, and it'd be a good idea to shop for low-VOC paint this time around. VOC stands for volatile organic compounds. Some VOCs are fungicides that prevent mold growth, others help with color and some contribute to the paint's spreadability. The fact of the matter is that chemicals like these have been part of the manufacturing process for many years because it actually made the paint better. Believe it or not, even toxic lead, which is no longer used, was there to improve colorfastness. In fact, I remember finding a can of very, very old paint during a home inspection years ago on which the manufacturer bragged about the paint's high lead content!Fortunately, the manufacturing process has gotten much better at producing quality paint that is much safer to use. Today, lead is gone and low- or no-VOC paint is the standard. Latex, alkyd-based paint is commonly made with no or low VOCs and even oil paints have a lot less. You can actually read the paint's label to determine how much VOC has been added. A low-VOC latex paint would have about 250 grams of VOCs, and a low oil-based paint would have about 350 grams or so. When shopping for paint, be sure to inform the clerk that you are particularly interested in low-odor, low-VOC paints. If you ever have a question about what is inside the can, you can also ask for the MSDS (Material Safety Data Sheet) which will list VOCs in Section 9. Odor is another issue that manufacturers have been working to reduce, and most low-VOC products are also low-odor.Other than selecting low-VOC paint, just make sure you work in a well-ventilated area. Opening up a few windows in the dead of winter might not seem like a smart idea, but the added cost in heat is a small price to pay for your health and comfort throughout the job.